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report thumbnailEurope Prothrombin Complex Concentrate (PCC) Market

Europe Prothrombin Complex Concentrate (PCC) Market 2025-2033 Analysis: Trends, Competitor Dynamics, and Growth Opportunities

Europe Prothrombin Complex Concentrate (PCC) Market by Product (4-factor PCC, 3-factor PCC), by Application (Acquired Coagulation Deficiency, Congenital Coagulation Deficiency, By End User (Hospitals & Ambulatory Surgical Centers, Specialty Clinics, Others), by Europe (United Kingdom, Germany, France, Italy, Spain, Netherlands, Belgium, Sweden, Norway, Poland, Denmark) Forecast 2026-2034

Jun 21 2025
Base Year: 2025
135 Pages
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Europe Prothrombin Complex Concentrate (PCC) Market 2025-2033 Analysis: Trends, Competitor Dynamics, and Growth Opportunities

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Europe Prothrombin Complex Concentrate (PCC) Market 2025-2033 Analysis: Trends, Competitor Dynamics, and Growth Opportunities

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Key Insights

The size of the Europe Prothrombin Complex Concentrate (PCC) Market was valued at USD 174.6 USD million in 2023 and is projected to reach USD 670.75 USD million by 2032, with an expected CAGR of 21.2% during the forecast period. The surge in dental procedures, coupled with the growing awareness of oral hygiene, has been the driving force behind this market's growth. The benefits of PCC, which include improved wound healing, reduced bleeding, and faster recovery time, have contributed to its popularity. Governments are promoting oral health initiatives, further fueling the market growth. Technological advancements in dental equipment and techniques are also shaping the market landscape. Major players like Colgate-Palmolive, Procter & Gamble, and Unilever dominate the market, offering various types of dental care products.

Europe Prothrombin Complex Concentrate (PCC) Market Research Report - Market Overview and Key Insights

Europe Prothrombin Complex Concentrate (PCC) Market Market Size (In Million)

500.0M
400.0M
300.0M
200.0M
100.0M
0
350.0 M
2021
375.0 M
2022
400.0 M
2023
425.0 M
2024
450.0 M
2025
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Europe Prothrombin Complex Concentrate (PCC) Market Trends

The European Prothrombin Complex Concentrate (PCC) market is experiencing dynamic growth, shaped by several converging trends. These include:

Europe Prothrombin Complex Concentrate (PCC) Market Market Size and Forecast (2024-2030)

Europe Prothrombin Complex Concentrate (PCC) Market Company Market Share

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Driving Forces: What's Propelling the Europe Prothrombin Complex Concentrate (PCC) Market

The Europe Prothrombin Complex Concentrate (PCC) Market is primarily driven by the following factors:

  • The rising prevalence of bleeding disorders, such as hemophilia and Von Willebrand disease.
  • The growing need for surgical interventions and trauma management, which require blood clotting factors.
  • The increasing awareness of PCC as a safe and effective treatment option.
  • The development of novel PCC products with improved efficacy and safety profiles.
  • Government initiatives and reimbursement policies that support PCC treatment.

Challenges and Restraints in Europe Prothrombin Complex Concentrate (PCC) Market

The Europe Prothrombin Complex Concentrate (PCC) Market faces certain challenges and restraints:

  • The high cost of PCC treatment, which can limit its accessibility for some patients.
  • The potential for allergic reactions and other adverse effects associated with PCC.
  • The availability of alternative treatment options, such as recombinant factor concentrates.
  • The stringent regulatory requirements for the manufacturing and distribution of PCC products.

Key Region or Country & Segment to Dominate the Market

Key Regions:

  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain

Dominating Segment:

Product Type: 4-factor PCC

4-factor PCC holds a significant market share due to its broad spectrum of activity and efficacy in treating various bleeding disorders.

Growth Catalysts in Europe Prothrombin Complex Concentrate (PCC) Industry

  • The development of new PCC products with extended half-lives and reduced immunogenicity.
  • The increasing focus on personalized medicine and tailored treatment approaches.
  • The growing adoption of point-of-care diagnostics for rapid and accurate diagnosis of bleeding disorders.
  • The expansion of home therapy programs for patients with chronic bleeding disorders.

Market Segmentation: Europe Prothrombin Complex Concentrate (PCC) Analysis

Product Type:

  • 4-factor PCC
  • 3-factor PCC

Application:

  • Acquired Coagulation Deficiency
  • Congenital Coagulation Deficiency

End User:

  • Hospitals & Ambulatory Surgical Centers
  • Specialty Clinics
  • Others

Leading Players in the Europe Prothrombin Complex Concentrate (PCC) Market

  • CSL Limited 
  • Grifols, S.A. 
  • Octapharma AG 
  • Kedrion S.p.A
  • Sanquin 
  • Takeda Pharmaceutical Company Limited 

Significant Developments in Europe Prothrombin Complex Concentrate (PCC) Sector

  • In 2021, CSL Limited received approval from the European Commission for its extended half-life PCC product, Idelvion.
  • In 2022, Octapharma AG launched Nuwiq, a novel 4-factor PCC with reduced immunogenicity.

Comprehensive Coverage Europe Prothrombin Complex Concentrate (PCC) Market Report

Our comprehensive report offers in-depth analysis of the European Prothrombin Complex Concentrate (PCC) market, providing valuable insights for stakeholders across the value chain. Key aspects covered include:

  • Regional Analysis: Detailed examination of market dynamics in key European countries, including market size estimations, growth projections, and competitive landscapes. Specific focus on leading markets like Germany, France, UK, Italy, and Spain.
  • Segment Analysis: Granular analysis by product type (e.g., three-factor PCC, four-factor PCC), indication (e.g., prophylaxis, treatment of bleeding episodes), and route of administration.
  • Competitive Landscape: In-depth profiles of key market players, assessing their market share, strategies, R&D pipelines, and competitive advantages. Analysis of mergers, acquisitions, and partnerships impacting the market.
  • Growth Drivers and Market Dynamics: Identification and analysis of key factors driving market growth, including regulatory landscape changes, pricing trends, and evolving clinical practices.
  • Challenges and Restraints: Evaluation of potential obstacles to market growth, such as pricing pressures, stringent regulatory approvals, and potential side effects of PCC therapies.
  • Future Outlook and Forecasts: Presentation of market projections based on current trends and anticipated future developments.

Regional Insight

Europe holds a dominant position in the global Prothrombin Complex Concentrate (PCC) market, driven by factors such as high prevalence of bleeding disorders, strong healthcare infrastructure, and favorable reimbursement policies. Germany, France, the United Kingdom, Italy, and Spain are key contributors to this market dominance, reflecting significant patient populations and well-established healthcare systems dedicated to treating bleeding disorders.

Europe Prothrombin Complex Concentrate (PCC) Market Market Share by Region - Global Geographic Distribution

Europe Prothrombin Complex Concentrate (PCC) Market Regional Market Share

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DROCT

Drivers:

  • Rising prevalence of bleeding disorders
  • Increasing demand for surgical interventions
  • Growing awareness of PCC treatment options

Restraints:

  • High cost of PCC treatment
  • Potential for adverse effects
  • Availability of alternative treatment options

Opportunities:

  • Development of new PCC products
  • Personalized medicine and tailored treatment approaches
  • Expansion of home therapy programs

Challenges:

  • Stringent regulatory requirements

Geographic Coverage of Europe Prothrombin Complex Concentrate (PCC) Market

Higher Coverage
Lower Coverage
No Coverage

Europe Prothrombin Complex Concentrate (PCC) Market REPORT HIGHLIGHTS

AspectsDetails
Study Period 2020-2034
Base Year 2025
Estimated Year 2026
Forecast Period2026-2034
Historical Period2020-2025
Growth RateCAGR of 21.2% from 2020-2034
Segmentation
    • By Product
      • 4-factor PCC
      • 3-factor PCC
    • By Application
      • Acquired Coagulation Deficiency
      • Congenital Coagulation Deficiency
      • By End User (Hospitals & Ambulatory Surgical Centers
      • Specialty Clinics
      • Others
  • By Geography
    • Europe
      • United Kingdom
      • Germany
      • France
      • Italy
      • Spain
      • Netherlands
      • Belgium
      • Sweden
      • Norway
      • Poland
      • Denmark

Table of Contents

  1. 1. Introduction
    • 1.1. Research Scope
    • 1.2. Market Segmentation
    • 1.3. Research Methodology
    • 1.4. Definitions and Assumptions
  2. 2. Executive Summary
    • 2.1. Introduction
  3. 3. Market Dynamics
    • 3.1. Introduction
      • 3.2. Market Drivers
        • 3.2.1. Increasing Public Awareness for Safer Medicines to Stimulate Market Value
      • 3.3. Market Restrains
        • 3.3.1. High Treatment Costs Associated with PCC to Impede Market Growth
      • 3.4. Market Trends
        • 3.4.1. Manufacturers focusing on the Development of Mitral Valve Product will drive the Market
  4. 4. Market Factor Analysis
    • 4.1. Porters Five Forces
    • 4.2. Supply/Value Chain
    • 4.3. PESTEL analysis
    • 4.4. Market Entropy
    • 4.5. Patent/Trademark Analysis
  5. 5. Europe Prothrombin Complex Concentrate (PCC) Market Analysis, Insights and Forecast, 2020-2032
    • 5.1. Market Analysis, Insights and Forecast - by Product
      • 5.1.1. 4-factor PCC
      • 5.1.2. 3-factor PCC
    • 5.2. Market Analysis, Insights and Forecast - by Application
      • 5.2.1. Acquired Coagulation Deficiency
      • 5.2.2. Congenital Coagulation Deficiency
      • 5.2.3. By End User (Hospitals & Ambulatory Surgical Centers
      • 5.2.4. Specialty Clinics
      • 5.2.5. Others
    • 5.3. Market Analysis, Insights and Forecast - by Region
      • 5.3.1. Europe
  6. 6. Competitive Analysis
    • 6.1. Market Share Analysis 2025
      • 6.2. Company Profiles
        • 6.2.1 CSL Limited (Melbourne Australia)
          • 6.2.1.1. Overview
          • 6.2.1.2. Products
          • 6.2.1.3. SWOT Analysis
          • 6.2.1.4. Recent Developments
          • 6.2.1.5. Financials (Based on Availability)
        • 6.2.2 Grifols S.A. (Barcelona
          • 6.2.2.1. Overview
          • 6.2.2.2. Products
          • 6.2.2.3. SWOT Analysis
          • 6.2.2.4. Recent Developments
          • 6.2.2.5. Financials (Based on Availability)
        • 6.2.3 Spain)
          • 6.2.3.1. Overview
          • 6.2.3.2. Products
          • 6.2.3.3. SWOT Analysis
          • 6.2.3.4. Recent Developments
          • 6.2.3.5. Financials (Based on Availability)
        • 6.2.4 Octapharma AG (Lachen Switzerland)
          • 6.2.4.1. Overview
          • 6.2.4.2. Products
          • 6.2.4.3. SWOT Analysis
          • 6.2.4.4. Recent Developments
          • 6.2.4.5. Financials (Based on Availability)
        • 6.2.5 Kedrion S.p.A (Lucca Italy)
          • 6.2.5.1. Overview
          • 6.2.5.2. Products
          • 6.2.5.3. SWOT Analysis
          • 6.2.5.4. Recent Developments
          • 6.2.5.5. Financials (Based on Availability)
        • 6.2.6 Sanquin (Amsterdam The Netherlands)
          • 6.2.6.1. Overview
          • 6.2.6.2. Products
          • 6.2.6.3. SWOT Analysis
          • 6.2.6.4. Recent Developments
          • 6.2.6.5. Financials (Based on Availability)
        • 6.2.7 Takeda Pharmaceutical Company Limited (Tokyo Japan)
          • 6.2.7.1. Overview
          • 6.2.7.2. Products
          • 6.2.7.3. SWOT Analysis
          • 6.2.7.4. Recent Developments
          • 6.2.7.5. Financials (Based on Availability)
        • 6.2.8 Other Prominent Players
          • 6.2.8.1. Overview
          • 6.2.8.2. Products
          • 6.2.8.3. SWOT Analysis
          • 6.2.8.4. Recent Developments
          • 6.2.8.5. Financials (Based on Availability)

List of Figures

  1. Figure 1: Europe Prothrombin Complex Concentrate (PCC) Market Revenue Breakdown (USD million, %) by Product 2025 & 2033
  2. Figure 2: Europe Prothrombin Complex Concentrate (PCC) Market Share (%) by Company 2025

List of Tables

  1. Table 1: Europe Prothrombin Complex Concentrate (PCC) Market Revenue USD million Forecast, by Product 2020 & 2033
  2. Table 2: Europe Prothrombin Complex Concentrate (PCC) Market Volume million units Forecast, by Product 2020 & 2033
  3. Table 3: Europe Prothrombin Complex Concentrate (PCC) Market Revenue USD million Forecast, by Application 2020 & 2033
  4. Table 4: Europe Prothrombin Complex Concentrate (PCC) Market Volume million units Forecast, by Application 2020 & 2033
  5. Table 5: Europe Prothrombin Complex Concentrate (PCC) Market Revenue USD million Forecast, by Region 2020 & 2033
  6. Table 6: Europe Prothrombin Complex Concentrate (PCC) Market Volume million units Forecast, by Region 2020 & 2033
  7. Table 7: Europe Prothrombin Complex Concentrate (PCC) Market Revenue USD million Forecast, by Product 2020 & 2033
  8. Table 8: Europe Prothrombin Complex Concentrate (PCC) Market Volume million units Forecast, by Product 2020 & 2033
  9. Table 9: Europe Prothrombin Complex Concentrate (PCC) Market Revenue USD million Forecast, by Application 2020 & 2033
  10. Table 10: Europe Prothrombin Complex Concentrate (PCC) Market Volume million units Forecast, by Application 2020 & 2033
  11. Table 11: Europe Prothrombin Complex Concentrate (PCC) Market Revenue USD million Forecast, by Country 2020 & 2033
  12. Table 12: Europe Prothrombin Complex Concentrate (PCC) Market Volume million units Forecast, by Country 2020 & 2033
  13. Table 13: United Kingdom Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  14. Table 14: United Kingdom Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  15. Table 15: Germany Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  16. Table 16: Germany Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  17. Table 17: France Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  18. Table 18: France Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  19. Table 19: Italy Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  20. Table 20: Italy Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  21. Table 21: Spain Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  22. Table 22: Spain Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  23. Table 23: Netherlands Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  24. Table 24: Netherlands Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  25. Table 25: Belgium Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  26. Table 26: Belgium Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  27. Table 27: Sweden Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  28. Table 28: Sweden Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  29. Table 29: Norway Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  30. Table 30: Norway Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  31. Table 31: Poland Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  32. Table 32: Poland Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033
  33. Table 33: Denmark Europe Prothrombin Complex Concentrate (PCC) Market Revenue (USD million) Forecast, by Application 2020 & 2033
  34. Table 34: Denmark Europe Prothrombin Complex Concentrate (PCC) Market Volume (million units) Forecast, by Application 2020 & 2033

Methodology

Step 1 - Identification of Relevant Samples Size from Population Database

Step Chart
Bar Chart
Method Chart

Step 2 - Approaches for Defining Global Market Size (Value, Volume* & Price*)

Approach Chart
Top-down and bottom-up approaches are used to validate the global market size and estimate the market size for manufactures, regional segments, product, and application.

Note*: In applicable scenarios

Step 3 - Data Sources

Primary Research

  • Web Analytics
  • Survey Reports
  • Research Institute
  • Latest Research Reports
  • Opinion Leaders

Secondary Research

  • Annual Reports
  • White Paper
  • Latest Press Release
  • Industry Association
  • Paid Database
  • Investor Presentations
Analyst Chart

Step 4 - Data Triangulation

Involves using different sources of information in order to increase the validity of a study

These sources are likely to be stakeholders in a program - participants, other researchers, program staff, other community members, and so on.

Then we put all data in single framework & apply various statistical tools to find out the dynamic on the market.

During the analysis stage, feedback from the stakeholder groups would be compared to determine areas of agreement as well as areas of divergence

Additionally, after gathering mixed and scattered data from a wide range of sources, data is triangulated and correlated to come up with estimated figures which are further validated through primary mediums or industry experts, opinion leaders.

Frequently Asked Questions

1. What is the projected Compound Annual Growth Rate (CAGR) of the Europe Prothrombin Complex Concentrate (PCC) Market?

The projected CAGR is approximately 21.2%.

2. Which companies are prominent players in the Europe Prothrombin Complex Concentrate (PCC) Market?

Key companies in the market include CSL Limited (Melbourne, Australia), Grifols, S.A. (Barcelona, Spain), Octapharma AG (Lachen, Switzerland), Kedrion S.p.A (Lucca, Italy), Sanquin (Amsterdam, The Netherlands), Takeda Pharmaceutical Company Limited (Tokyo, Japan), Other Prominent Players.

3. What are the main segments of the Europe Prothrombin Complex Concentrate (PCC) Market?

The market segments include Product, Application.

4. Can you provide details about the market size?

The market size is estimated to be USD 174.6 USD million as of 2022.

5. What are some drivers contributing to market growth?

Increasing Public Awareness for Safer Medicines to Stimulate Market Value.

6. What are the notable trends driving market growth?

Manufacturers focusing on the Development of Mitral Valve Product will drive the Market.

7. Are there any restraints impacting market growth?

High Treatment Costs Associated with PCC to Impede Market Growth.

8. Can you provide examples of recent developments in the market?

N/A

9. What pricing options are available for accessing the report?

Pricing options include single-user, multi-user, and enterprise licenses priced at USD 3850, USD 4850, and USD 5850 respectively.

10. Is the market size provided in terms of value or volume?

The market size is provided in terms of value, measured in USD million and volume, measured in million units.

11. Are there any specific market keywords associated with the report?

Yes, the market keyword associated with the report is "Europe Prothrombin Complex Concentrate (PCC) Market," which aids in identifying and referencing the specific market segment covered.

12. How do I determine which pricing option suits my needs best?

The pricing options vary based on user requirements and access needs. Individual users may opt for single-user licenses, while businesses requiring broader access may choose multi-user or enterprise licenses for cost-effective access to the report.

13. Are there any additional resources or data provided in the Europe Prothrombin Complex Concentrate (PCC) Market report?

While the report offers comprehensive insights, it's advisable to review the specific contents or supplementary materials provided to ascertain if additional resources or data are available.

14. How can I stay updated on further developments or reports in the Europe Prothrombin Complex Concentrate (PCC) Market?

To stay informed about further developments, trends, and reports in the Europe Prothrombin Complex Concentrate (PCC) Market, consider subscribing to industry newsletters, following relevant companies and organizations, or regularly checking reputable industry news sources and publications.